Friday, 19 July 2013

NATURAL MIRACLES ; TOP 10 MEDICINAL PLANTS AND HERBS

Plants are the most amazing gifts given by nature to humans .Many of these plants are consists of medicinal properties according to a study there are more than 3000 plants in the world .As we all know that natural therapy has lesser number of side effect as compared to chemicals . Therefore to increase the awareness for natural plants I present you the TOP 10 MEDICINAL PLANTS OF WORLD . These medicinal herbs are used by us humans from the medieval period.Our ancestors knows the better use of these medicinal plants to tackle the diseases burns and cuts.
Aloe Vera
Kingdom : Plantae
Family: Xanthorrhoeaceae
Aloe vera is a stemless or very short-stemmed succulent plant growing to 60–100 cm (24–39 in) tall, spreading by offsets. The leaves are thick and fleshy, green to grey-green, with some varieties showing white flecks on their upper and lower stem surfaces.This medicinal plant can be used to heal the burns,wounds. The bottom stalk of the aloe vera can be used as a balm on the burn thereby relieving you instantly. Besides this the plant can be used in the treatment of eczema and reducing inflammation. This can also be eaten to treat digestive problems, ulcerative colitis, chronic constipation and poor appetite.

Marijuana
Source : Cannabis sativa, Cannabis indica, Cannabis ruderalis
Main producers: Afghanistan, Burma, Canada, China, Colombia, India, Jamaica, Laos, Mexico, Netherlands, Pakistan, Thailand, Turkey, United States
 Cannabis, also known as marijuana (from the Mexican Spanish marihuana), and by numerous other names, a preparation of the Cannabis plant intended for use as a psychoactive drug and as medicine.Cannabis is most often consumed for its psychoactive and physiological effects which can include heightened mood or euphoria, relaxation, and increase in appetite.According to a 2011 study published in the American Journal of Epidemiology, obesity is lower in cannabis users than in nonusers. Authors of the study looked at data from two representative epidemiological studies for US citizens aged 18 and over.Cannabis is known for inducing hunger, but two cannabinoids, THCV and cannabidiol, were found to have an appetite suppressing effect. In animal tests, the drug also had an impact on the level of fat in the body as well as its response to insulin.
Holy Basil (Tulsi) 
Kingdom:Plantae
Species:O. tenuiflorum
Ocimum tenuiflorum, also known as Ocimum sanctum, Holy basil, or tulasī, is an aromatic plant in the family Lamiaceae which is native throughout the Eastern World tropics and widespread as a cultivated plant.It is an erect, much branched subshrub, 30–60 cm tall with hairy stems and simple opposite green or purple leaves that are strongly scented. Leaves have petioles and are ovate, up to 5 cm long, usually slightly toothed. The flowers are purplish in elongate racemes in close whorls. The two main morphotypes cultivated in India and Nepal are green-leaved (Sri or Lakshmi tulasi) and purple-leaved (Krishna tulasi). It is also worshiped in some parts of indian and regarded as sacred. Coming back to its medicinal uses it is used for to bring down fever, to fight cold and flu, tulsi oil can be used as a potent anti malarial drug, it can be used to reduce earache. Moreover it also increases the antibody production of the body.
Great Burdock
Kingdom:Plantae
Species:A. lappa
Arctium lappa, commonly called greater burdock, gobō,edible burdock lappa,or beggar's buttons,is a biennial plant[citation needed] of the Arctium (burdock) genus in the Asteraceae family, cultivated in gardens for its root used as a vegetable. It is an invasive weed of high-nitrogen soils.This plant finds its use in some traditional way and is used as a blood purifying agent and so it helps in fighting the skin diseases. The flowers of this plant are purple and green in color which adds as an aesthetic use of this plant.Other uses for this medicinal plant include boils, rashes, bruises, burns, acne, ringworm and bites.The flowers are purple and grouped in globular capitula, united in clusters. They appear in mid-summer, from July to September.The capitula are surrounded by an involucre made out of many bracts, each curving to form a hook, allowing them to be carried long distances on the fur of animals. 
Echinacea
Kingdom:Plantae
Genus:Echinacea
Echinacea is a genus, or group of herbaceous flowering plants in the daisy family, Asteraceae. The nine species it contains are commonly called coneflowers. They are endemic to eastern and central North America, where they are found growing in moist to dry prairies and open wooded areas. They have large, showy heads of composite flowers, blooming from early to late summer. The generic name is derived from the.Some species are used in herbal medicines and some are cultivated in gardens for their showy flowers.Echinacea is a flowery medicinal herb which is still considered to be the most important herb for the treatment of burns,cuts and wounds. It is a herbaceous plant it also finds its use as a handy medicine which can be applied for treatment of sores, burns, wounds, allergy relief, insect bites, stings and snakebites. This can be used for energy relief and it strengthens the immune system of the body.
Sage:
Kingdom:Plantae
Species:S. officinalis
Salvia officinalis (sage, also called garden sage, or common sage) is a perennial, evergreen subshrub, with woody stems, grayish leaves, and blue to purplish flowers. It is a member of the family Lamiaceae and is native to the Mediterranean region, though it has naturalized in many places throughout the world. It has a long history of medicinal and culinary use, and in modern times as an ornamental garden plant. The common name "sage" is also used for a number of related and unrelated species.Sage is a plant which can be used for both purposes cooking as well as for medicinal purposes. Sage has got its name from a latin word sage where it means “heal”. So as per its name the healing property of this medicinal plant lies in curing skin infections, gum infections and mouth infections. It can also help with indigestion, flatulence, depression and even menopausal problems. This also acts as a good salve for insect bite.
Blackberries
Kingdom:Plantae
Species:Rubus fruticosus
The blackberry is an edible fruit produced by many species in the Rubus genus in the Rosaceae family, hybrids among these species within the Rubus subgenus, and hybrids between the Rubus and Idaeobatus subgenera. What distinguishes the blackberry from its raspberry relatives is whether the torus (receptacle) picks with the fruit, a blackberry, or remains on the plant when picked, leaving a hole in the fruit, a raspberry. The term 'bramble', a word meaning any impenetrable scrub, has traditionally been applied specifically to the blackberry or its products,though in the United States it applies to all members of the Rubus genus. With its taste and its use in our food in the form of jam or as an vegetable, Blackberries enriched with antioxidants and vitamins has also various uses as medicines. The leaves and root can be used as an effective treatment against dysentery and diarrhea as well as can be served as an anti-inflammatory and astringent. This plant is ideal for treating cuts and inflammation in the mouth therefore can be used as a substitute of Glycerin.
Peppermint 
Kingdom:Plantae
Family:Lamiaceae
Peppermint (Mentha × piperita, also known as M. balsamea Willd.) is a hybrid mint, a cross between watermint and spearmint. The plant, indigenous to Europe, is now widespread in cultivation throughout all regions of the world. It is found wild occasionally with its parent species.Best smelling plant of all time whenever you feel low the mint candy always help you in keeping your spirits high. It sends a cooling sensation from your throat to your esophagus. This medicinal plant finds its application from the ancient times. This plant is naturally enriched with Vitamin A , C and manganese. It is also very helpful  in reducing number of symptoms including irritable bowel syndrome, upset stomachs, fevers, flatulence and spastic colon.
Tea Tree
Kingdom:Plantae
Species:M. alternifolia
Melaleuca alternifolia, commonly known as Narrow-leaved Paperbark, Narrow-leaved Tea-tree, Narrow-leaved Ti-tree, or Snow-in-summer, is a species of tree or tall shrub in the plant genus Melaleuca. Native to Australia, it occurs in Southeast Queensland and the north coast and adjacent ranges of New South Wales. It grows along streams and on swampy flats, and is often the dominant species where it occurs.Ask any beautician or read the over cover of any beauty product for its ingredients you will definitely find Tea Tree oil. This exactly shows how much important that tea tree oil is for medicinal purposes. This medicinal plant’s oil is extracted from its leaves and twigs. It has many uses including the treatment of acne, vaginal infections,insect bites, cold sorts,warts,minor burns,thrush and other syndromes like chronic fatigue.
Ginseng
Kingdom:Plantae
Genus:Panax
Ginseng is found only in the Northern Hemisphere, in North America and in eastern Asia (mostly Korea, northeastern China (Manchuria), Bhutan, and eastern Siberia), typically in cooler climates. Panax vietnamensis, discovered in Vietnam, is the southernmost ginseng known. This article focuses on the series Panax ginsengs, which are the adaptogenic herbs, principally Panax ginseng and P. quinquefolius. Ginseng is characterized by the presence of ginsenosides.Ginseng is the medicinal plant which has its popularity in the eastern part of the world .This herb has many uses, besides this it can be said to be focused on the general health of the homo sapiens instead of being useful only for a particular type of ailment.The root of Ginseng is used for nervous system relaxation. the leaves of this plant is used to improve your immune system as well as stamina. It also helps in reducing cholesterol levels and also in treatment of lack of appetite and insomnia.

So these were the plants which I think are the most widely used for medicinal purpose may be you have another list or there may be other suggestions also so please suggest me in the comments. 




Saturday, 13 July 2013

ONE WHO DESIGNED FUTURE :WORLDS MOST FAMOUS PHARMACISTS

Tell me one thing have anyone of you have ever searched about worlds great pharmacists? .yesterday as i was walking around i met a b tech a student we were not familiar with  each other but we started talking in a middle of talk he asked me a question that as per your profession how many great pharmacist you can name i was totally numb  i can't name more than two. so this gave me idea to put a post about great pharmacist .so who is a pharmacist? in my opinion anyone who deals with use,discovery and sales of pharmaceutical compound is a pharmacist . so lets talk about persons who made it.
Ibn al-baitar:man who discovered anticancers 

He was one of the greatest scientists of Muslim Spain and an eminent botanist and pharmacist during the Middle Ages. He was born in the  Spanish city of Benalmadena, near Malaga, towards  the end of the 12th century. He received his education as a physician in Seville, under the guidance of Abul Abbas Ahmad. He developed a great interest in  botany, which he learned from his teacher, who was  also a botanist. He started collecting plants in and  around Andalusia. In 1219, he left Spain on a plant collecting expedition and travelled along the northern  coast of Africa, as far as Asia Minor. his most remarkable achievements was  the discovery of the anti-cancer effects of the plant named hindiba as having “anti-cancer” properties and which can be  used to treat tumors and neoplastic disorders. After  its usefulness in the treatment of neoplastic disorders  was recognized, Hindiba was patented in 1997 by Nil Sari, Hanzade Dogan, and John K. Snyder.In the year 1224 CE, he entered the service of Malik al-Kamil, the Egyptian ruler, and was appointed chief herbalist.Al-Kamil extended his kingdom to  Damascus, and Ibn al-Baitar accompanied him there,  which provided him with an opportunity to collect  plants in Syria, Palestine, and many parts of Iraq
AL RAZI:Introduce chemicals to world
Muhammad ibn Zakariyā Rāzī  Abu Bakr Mohammad Bin Yahia Bin Zakaria Al-Razi Mohammad-e Zakariā-ye Rāzi, known as Rhazes or Rasis after medieval Latinists (August 26, 865 – 925), was a Persian Muslim polymath, a prominent figure in Islamic Golden Age physician, alchemist and chemist, philosopher, and scholar. Numerous "firsts" in medical research, clinical care, and chemistry are attributed to him, including being the first to differentiate smallpox from measles, and the discovery of numerous compounds and chemicals including alcohol, kerosene, among others.Edward Granville Browne considers him as "probably the greatest and most original of all the physicians, and one of the most prolific as an author". Razi made fundamental and enduring contributions to the fields of medicine, alchemy, music, and philosophy, recorded in over 200 books and articles in various fields of science. He was well-versed in Ancient Persian, Greek and Ancient Indian medical knowledge and made numerous advances in medicine through own observations and discoveries
Arthur D. Levinson:Chairman of Apple.inc
Arthur D. Levinson (born March 31, 1950) is the chairman of Genentech (1999 to present) and the chairman of Apple Inc. (2011 to present). He is the former chief executive officer of Genentech (1995–2009) and is also a member of Genentech’s Scientific Research Board, which serves as an advisory group to the company regarding its research and early development projects.In addition to serving as Chairman for Genentech and Apple. Inc., Levinson serves on the Board of Directors of F. Hoffmann-La Roche Ltd, NGM Biopharmaceuticals, Inc., Amyris Biotechnologies, Inc. and the Broad Institute of MIT and Harvard. He currently serves on the Board of Scientific Consultants of the Memorial Sloan-Kettering Cancer Center, the Industrial Advisory Board of the California Institute for Quantitative Biosciences (QB3), the Advisory Council for the Princeton University Department of Molecular Biology and the Advisory Council for the Lewis-Sigler Institute for Integrative Genomics.


Caleb Davis Bradham:Pepsi man
invented the soft drink Pepsi-Cola. He was a pharmacist, born in Chinquapin, Duplin County, North Carolina, May 27, 1867. He graduated from the University of North Carolina at Chapel Hill where he was a member of the Philanthropic Society, and attended the University of Maryland School of Medicine. Circa 1890, he dropped out of the University of Maryland School of Medicine, owing to his father's business going bankrupt. After returning to North Carolina, he was a public school teacher for about a year, and soon thereafter opened a drug store in New Bern named the "Bradham Drug Company" that, like many other drug stores of the time, also housed a soda fountain.  Bradham named his drink after a combination of the terms “pepsin” and “cola,” as he believed that his drink aided digestion much like the pepsin enzyme does, even though it was not used as an ingredient. His assistant James Henry King was the first to taste the new drink.

On December 24, 1902, the Pepsi-Cola Company was incorporated in North Carolina, with Bradham as the president, and on June 16, 1903 the first Pepsi-Cola trademark was registered. Also in 1903, he moved his Pepsi-Cola production out of his drug store and into a rented building nearby. In 1905, Bradham began selling Pepsi-Cola in six-ounce bottles (up until this time he sold Pepsi-Cola as a syrup only), and awarded two franchises to North Carolina bottlers.
Ignacy Lukasiewicz:  worlds first oil refinery
Jan Józef Ignacy Lukasiewicz (Polish pronunciation: [wukaˈɕɛvʲitʂ]; 1822–1882) was a Polish pharmacist and petroleum industry pioneer who in 1856 built the first oil refinery in the world..Among his other achievements were the discovery of how to distill kerosene from seep oil, the invention of the modern kerosene lamp (1853), the introduction of the first modern street lamp in Europe (1853), and the construction of the first world modern oil well (1854). Łukasiewicz became a wealthy man and one of the most prominent philanthropists in Galicia. Because of his support for the economical development of the region, a popular saying was coined attributing all paved roads to his guldens. In early 1854 Łukasiewicz moved to Gorlice, where he continued his work. He set up many companies together with entrepreneurs and landowners. That same year, he opened the world's first oil "mine" at Bóbrka, near Krosno (still operational as of 2006). At the same time Łukasiewicz continued his work on kerosene lamps. Later that year he set up the first kerosene street lamp in Gorlice's borough of Zawodzie. In the following years he opened several other oil wells, each of them as a joint-venture with various local merchants and businessmen The refinery was destroyed in a fire in 1859, but was rebuilt in Polanka[disambiguation needed] near Krosno the following year.
John Pemberton
John Stith Pemberton (July 8, 1831 – August 16, 1888) was a Confederate veteran and an American pharmacist, and is best known for being the inventor of Coca-Cola. he became addicted to morphine which he used to ease the pain. He was a pharmacist and as such searched for a cure to counteract this addiction. He began experimenting with coca and coca wines, eventually creating his own version of Vin Mariani, containing kola nut and damiana, which he called Pemberton's French Wine Coca. With public concern about drug addiction, depression and alcoholism among veterans, and "neurasthenia" among "highly-strung" Southern women,his medicinal concoction was advertised as being particularly beneficial for "ladies, and all those whose sedentary employment causes nervous prostration, irregularities of the stomach, bowels and kidneys, who require a nerve tonic and a pure, delightful diffusible stimulant"

As i described mens in my post but this list will never be complete if i dnt talk about the womens involved  in this noble profession  so lets count on womens
Dora Akunyili : She lives for pharmacology
Dora Nkem Akunyili (born July 14, 1954 in Makurdi, Benue State) is the former Director General of National Agency for Food and Drug Administration and Control (NAFDAC) of Nigeria and former (December 17, 2008 - December 15, 2010) Nigerian Minister of Information and Communications. She is a pharmacist and governmental administrator who has gained international recognition and won hundreds of awards for her work in pharmacology, public health and human rights Since Akunyili took over leadership of NAFDAC, she has established as a top priority the eradication of counterfeit drugs and unsafe food.[Before Akunyili assumed duty, Nigeria became a place where fake and substandard foods and drugs were being dumped without any form of regulations. She became angry because “so many of (her) countrymen and women (were) fighting killer diseases like malaria and tuberculosis with little more than sugar syrup and chalk tablets, cynically packaged to look like the real thing.” Although Akunyili has faced considerable risk to her personal safety in order to combat the issue of fake drugs, “She [has been] dancing with danger. And she [has been collecting] very visibly awards all over the world appearing with whomever has a smile to share
Molly Stevens : a professor
Molly Stevens is currently Professor of Biomedical Materials and Regenerative Medicine and the Research Director for Biomedical Material Sciences in the Institute of Biomedical Engineering at Imperial College. She joined Imperial in 2004 after a Postdoctoral training in the laboratory of Professor Robert Langer in the Chemical Engineering Department at the Massachusetts Institute of Technology (MIT). Prior to this she graduated from Bath University with a First Class Honours degree in Pharmaceutical Sciences and was then awarded a PhD in biophysical investigations of specific biomolecular interactions and single biomolecule mechanics from the Laboratory of Biophysics and Surface Analysis at the University of Nottingham (2000). In 2010 she was recognised by The Times as one of the top ten scientists under the age of 40 and also received the Polymer International-IUPAC award for creativity in polymer science, the Rosenhain medal and the Norman Heatley Prize for Interdisciplinary research from the Royal Society of Chemistry. In 2009 she was awarded the Jean Leray Award from the European Society for Biomaterials, in 2007 the prestigious Conference Science Medal from the Royal Pharmaceutical Society and in 2005 the Philip Leverhulme Prize for Engineering. She has also recently been recognised by the TR100, a compilation of the top innovators, under the age of 35, who are transforming technology - and the world with their work. Her previous awards include the Ronald Belcher Memorial Lecture Award from the Royal Society of Chemistry (2000) and both the Janssen Prize and the UpJohn Prize for academic excellence and research. 
Marla Ahlgrimm:First to identify hormone testing

Marla Ahlgrimm is an American entrepreneur, author, philanthropist, pharmacist and expert in women’s hormonal health. She is the author of The HRT Solution: Optimizing Your Hormone Potential which details the benefits of bioidentical hormone therapy and the book Self-Help For Premenstrual Syndrome. She is a frequent lecturer, has been featured as an expert in numerous professional journals and consumer magazines and has appeared on regional and national television and radio broadcasts. Ahlgrimm is the co-founder of Madison Pharmacy Associates, the first pharmacy in the United States devoted to women’s health.She is also the founder of Women’s Health America and is currently the President of Cyclin Pharmaceuticals.Ahlgrimm began her career at a local pharmacy in Madison, Wisconsin. During her time there, she identified symptoms that affected some of her patients severely. She identified these symptoms as premenstrual syndrome (PMS), prior to PMS being widely used as a term in the United States.Her early research was inspired by British physician Dr. Katharina Dalton who coined the term PMS during the 1950s.
Ahlgrimm co-founded Madison Pharmacy Associates in 1982. Madison Pharmacy Associates was the first pharmacy in the United States specializing in women’s health. She is considered a pioneer in the diagnosis and treatment of premenstrual syndrome, developing many of the bioidentical hormone therapy prescription options used today for hormone imbalance. She was one of the first to identify hormone testing options to understand individual hormone levels in women allowing for customization of hormone dosing. Ahlgrimm and her staff at Madison Pharmacy Associates provided care to women concerned with PMS, perimenopause, menopause, as well as specialized nutritional supplements and low dose, customized natural hormone prescription therapy. In 1997, she purchased competitor Bajamar Pharmacy, whose vice president praised Ahlgrimm stating, "She's more dedicated to women's health than anyone else I've met.
Janette Roberts
Jan has spent more than 40 years in the health care industry, almost 30 of those working in the area of women’s reproductive health. She is a Pharmacist with a postgraduate diploma in Clinical Nutrition and the Australian representative for Foresight the British Association famous for its work in promoting preconception health care. As coauthor of the international best selling series The Natural Way to Better Babies …Better Pregnancy … Better Birth & Bonding … and Better Breastfeeding, Jan has presented ‘preconception’ and ‘wellness’ workshops and seminars to the general public and health professionals around Australia, NZ and US since 1987. She has made frequent appearances on radio and TV and is a regular contributor to various magazines and journals.Jan was the co‐founder of one of the first Wellness Centres in Australia, later becoming the Director of Integrative Medicine at Spa Chakra ‐ Australia’s premier day spa where she developed programs for preconception, anti‐ageing, vitality and longevity. As Director of Well 4 life and Well 4 work she has provided educational material and complementary programs, services and products that support individual clients and corporations in their quest for total health and well being.

so these were few persons from the group of thousands of great personalities .hope all of you like the post and i am also sure that you must have few great name with you so please dnt forget to mention them in the comment box

Sunday, 7 July 2013

DRUG COMBINATIONS THAT CAN REALLY MESS YOU UP


Drug combinations 

Mixing some of the  drugs together is a bit like throwing a Molotov cocktail at your own body. If you’re reading You already know that substances of abuse can make a mess of people's lives. There are dozens of chemicals that can render you friendless, jobless and despondent—if not outright kill you—all by themselves. That makes mixing them together a bit like throwing a Molotov cocktail at your own body.
Too much of drug A may cause liver failure, say. Add a little of drug B and it might happen two hours sooner. Toss in drug C, and maybe you’ll stop breathing before your liver even gets involved.
Because every person reacts slightly differently, there’s virtually no way to determine which drug combination is most likely to land you, personally, in a body bag. But that doesn’t mean some pairings aren't deadlier than others. Some—like the painkiller/anti-anxiety drug/sleeping pill cocktail that killed Heath Ledger, and has been soaring in drug use stats—terrify even medical professionals.


·         1. Alcohol and benzodiazepines
One of the most common factor when Benzodiazepines are taken with alcohol is that the user forgets how much medication that they have taken and he or she continues to take more and more of the drug.
The reason is that the Alcohol is depressant and benzodiazepines such as ativan, valium and xanax are also depressants. The result of taking these two substance in combination can lead to depressed central nervous system, loss of consciousness and coma. Together, these two substances pose a potentially lethal risk to the user.

Xanax and alcohol are both Central Nervous System (CNS) depressants. (The central nervous system includes the brain and spinal cord.) They work by slowing down the brain, and subsequently, many other body systems. Xanax and alcohol both affect the crucial area of your brain called the hypothalamus. The hypothalamus is responsible for regulating heart rate, breathing rate, blood pressure, temperature, and many other vital functions. When Xanax and alcohol are taken together, the additive effects can lead to dangerously slowed breathing and heart rates.

2. Alcohol and prescription painkillers (Opioids with Alcohol)

Opioids are also considered CNS depressants, so they will react with alcohol in a similar way as depressant drugs react with alcohol. In addition to sedation, many opioids inhibit the coughing reflex, which places an individual at high risk for aspiration, pneumonia an choking. This creates a dangerous effect that could stop breathing altogether.
Opioids include Vicodin, Percocet, OxyContin, Opana, and Dilaudid.
Alcohol and opioids together cause sleepiness and poor concentration. You should avoid alcohol completely when you first start on opioids or when your dose has just been increased. If you are taking opioids, you should avoid alcohol if you are going to drive or operate machinery. When you get on a steady dose of opioid.
Taking opioids with alcohol can cause a dangerous reaction including slowed breathing and overdose. Drowsiness can be magnified by patients who take opioids with other narcotics, allergy medication, tranquilizers and sleeping pills.An allergic reaction is also possible with opioids and signs include:
  • Rash
  • Wheezing
  • Difficult breathing
  • C closing of the throat
  • Hives or swelling of the lips, face, tongue or throat.
Any of these serious side effects should prompt a visit to the emergency room.

Cocaine Combos
·         3. Cocaine and opiates
The combination remains just as dangerous as ever. “So many different things—seizures, heart attacks, strokes, unregulated body temperature—can happen when you take drugs that stimulate you, like cocaine," And then, on the other side you have the respiratory depression. If you have a combination of the two, it can make it harder for you to recognize the impact of one chemical.”
Is is a common misconception that uppers/stimulants a very dangerous when mixed with downers/opiates. I've had numerous doctors tell me this is not true but rather an assumption evolved out of the danger of speedballing(cocaine+heroin).

Mixing and upper with a downer is not harmful in SMALL amounts. EX: taking Adderal (mixed amphetamine sulfate salts) 60mg/day as well as 12mg of dilaudid (hydromorphone). Adderal is a strong stimulant and dilaudid is a very strong pain killer. I too once thought the combo was harmfull but  dr and pharm both said they are not the least harmfull when taken in PRESCRIBED amounts. It's when the two are mixed in large amounts that they become dangerous.

The Same goes for a speedball (cocaine an combo) people dont die from the combo but rather they die from doing LARGE amounts of either or both drugs.

·         4. Cocaine and ecstasy
Just like combining two depressants, combining two stimulants can exacerbate the effects of both. Though you’ll hardly fall asleep and stop breathing on this drug cocktail, you might well stop breathing in another way. Ecstasy on its own can damage the cardiovascular system and cause problems with body temperature regulation, and cocaine can do the same. If you're dancing at a hot sweaty club or a summer music festival while taking both, you’re pretty much asking to overheat or have a stroke.
What’s more, these two drugs frequently come cut; you really have no idea what you’re getting. As “Combining any unknown with any other unknown? It’s like Russian roulette.”

Coke and E don't really mix together. Both alone will raise your heart rate pretty high, taking both together will jack your heart rate up way too high. You can try it, but it's not suggested. Keep them separate and enjoy them for what they are. If you really want to mix your E with something, smoke some herb a little after you peak, it'll bring you back up for a while and you'll really enjoy your roll.

·         5. Alcohol and cocaine
. When you take cocaine and the alcohol together for a long time, there’s a combination chemical called cocaethylene that is formed that is very toxic,It can really damage your liver and heart and other organs.
Stimulant drugs such as cocaine, Ritalin, or meth can have detrimental effects on your body when combined with alcohol. In fact, mixing stimulants with alcohol is more dangerous than alcohol consumption alone because stimulants give users a false sense of sobriety. You might feel that you are not as drunk as you actually are and then drink beyond your physical limit. Or worse, stimulants can even hide the signs of an overdose. This delusion causes individuals to consume much more alcohol than normal.

While alcohol and cocaine used separately can cause serious health problems, combining the two can cause far greater risks.  When alcohol and cocaine are used together they create a third chemical, cocaethylene, to form in the liver.  This phenomena is the only known example of a formation of a third chemical forming in the body following the ingestion of two others.   The existence of cocaethelyne is basically unknown to those outside the pharmacological community. Some users report that it creates a feeling of higher euphoria , however, it is involved in 60% of sudden cocaine deaths. It has cardiovascular toxicity (i.e. leads to heart attack and strokes) so this combination should be avoided if you have a heart condition!

All-Rx Combos
·         6. Benzodiazepines, narcotic painkillers and sleeping pills
     Benzodiazepines, narcotic painkillers and sleeping pills Combining any central nervous system depressant—think OxyContin, Xanax, alcohol or heroin—with any other is a recipe for disaster. Their additive effects suppress breathing, and you might not notice. Your brain has a reward system that tells you if you’re getting high, and then it has a system that controls your breathing that’s located in the brainstem, and the two centers do not necessarily talk to each other.

“Trying to gauge how much you use based on how you feel is going to be deadly.” So why these three? In addition to the extremely addictive properties of benzos, sleeping pills and painkillers, this medley is particularly nasty because of its sheer prevalence.

·         7. Multiple prescription painkillers
Another in the multiple-depressant category, this one is again due to likelihood of respiratory failure and the high incidence of addiction. “Narcotics used for pain are not very effective after about six weeks,"
people adding drugs all the time, or increasing the amounts they’re taking over what’s been prescribed.  Also, the perception that all pills prescribed by a doctor are safe can give users a false sense of security. opioids were involved in more overdose deaths than cocaine and heroin combined.

·         8. Tylenol 3 and over-the-counter Tylenol


Tylenol doesn’t sound so scary—heck, doctors give it to babies—but it contains acetaminophen, which can be extremely toxic to the liver in high doses. That’s bad to take with any drug, but if you mix it with an addictive opioid—like Tylenol 3 with codeine—your liver is going to take a beating. According to a 2005 study from the University of Washington Medical Center in Seattle, 38% of people who developed acute liver failure because of accidentally ingesting too much had taken more than one kind of pill—and 63% had taken a pill that contained both acetaminophen and an opioid. You can't be too careful.